Tyrosine Kinases in Cancer
نویسندگان
چکیده
Articles should focus on tyrosine kinases in cancer and may include the following topics: Tyrosine kinases. § § Includes both tyrosine kinases and receptor tyrosine kinases, roles, including extracellular and intracellular signaling cascades. Aberrant tyrosine kinases § § Abnormalities including point mutations, chromosomal translocations and downstream effects of constitutive activation. Disease § § Roles in cancer, including solid and haematological malignancies, the use of tyrosine kinase inhibitors (TKIs) and resistance to TKIs. This supplement is intended to focus on tyrosine kinases in cancer. Aberrant tyrosine kinases and disease are included within the supplement’s scope.
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